The Joint Clinical Research Centre (JCRC) in Kakira, Uganda, is one of eight Regional Centres of Excellence (RCE). It was founded in 2004 during the PEPFAR I roll-out of antiretroviral treatment which was funded by USAID as part of the Timetable for Regional Expansion of ART (TREAT) project. The Kakira RCE still operates as an implementing entity for the USAID funded projects, but is now also involved in research collaborations with other international agencies including the MRC (UK) and ACTG. The Kakira RCE has 24 members of staff and two volunteers.
The clinic at the RCE treats patients with HIV and related infectious diseases. As of the 1st of January 2011, there were 850 HIV positive patients on follow-up in this clinic, of whom 714 patients are currently on first-line treatment, and 44 patients have been started on second-line therapy.
The JCRC Kakira site has participated in many clinical research studies including studies conducted by the International Aids Vaccine Initiative (IAVI, 2003/4), Malaria studies (2004) and the RAND study (2008/9). The key EARNEST site personnel are Prof. Peter Mugyenyi (PI), Dr. Samuel Kiirya (Co-PI), Dr.Luke Lakidi (Trial manager), Charles Draleku (Laboratory Manager), Richard Ruganda (Data Manager), Agnes Nankya (Trial Nurse) and Samuel Kafuma (Trial Dispenser).
More information on JCRC can be obtained via http://www.jcrc.co.ug